Author

B. T. Spear

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Poupeau· 1 shared C. Turpin· 1 shared E. Gatineau· 1 shared E. Lee· 1 shared F. Yiannikouris· 1 shared G. Arthur· 1 shared G. Graf· 1 shared G. Qiu· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. Poupeau

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2 papers

Recent·Most cited

Zinc Fingers and Homeoboxes 2 is Required for Diethylnitrosamine-induced Liver Tumor Formation in C57BL/6 Mice

J. Jiang, C. Turpin, G. Qiu, M. Xu, E. Lee, T. D. Hinds, M. L. Peterson, B. T. Spear

This study shows that Zhx2 acts as an oncogene in a liver tumor model, contradicting previous findings in human cell lines and other models, and correlates with higher ZHX2 expression in HCC patients.

bioRxiv · Sep 2, 2022Cancer Biology

The Prorenin Receptor and its Soluble Form Contribute to Lipid Homeostasis

E. Gatineau, G. Arthur, A. Poupeau, K. M. Nichols, B. T. Spear, G. Graf, R. E. Temel, F. Yiannikouris

This study investigates the role of PRR and its soluble form sPRR in lipid homeostasis, finding that hepatic PRR deletion increases cholesterol and sPRR levels, suggesting sPRR contributes to lipid metabolism and adipose-liver communication.

bioRxiv · Jan 27, 2020Physiology