Author

G. Arthur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Poupeau· 2 shared A. Loria· 1 shared A. S. Loria· 1 shared B. T. Spear· 1 shared E. Gatineau· 1 shared F. Yiannikouris· 1 shared G. Graf· 1 shared J. Osborn· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPhysiology

A. Poupeau

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Author profile →

4 papers

Recent·Most cited

Renal-Derived Human sPRR Does Not Increase Blood Pressure in High Fat Diet Mice

G. Arthur, K. Biel, J. Osborn, T. D. Hinds, M. Gong, A. Loria

This study investigates whether renal-derived human sPRR affects blood pressure and kidney function in obese mice, finding no overall effect but sex-specific differences in male mice.

bioRxiv · Jan 30, 2024 · PreprintPhysiology

Human Soluble Prorenin Receptor Expressed in Adipose Tissue Improves Insulin Sensitivity and Endothelial Function in Obese Female Mice

G. Arthur, N. Ahmed, K. Nichols, A. Poupeau, K. Collins, V. Lindner, A. S. Loria

This study shows that human sPRR expressed in adipose tissue improves insulin sensitivity and endothelial function in obese female mice, but not in males.

bioRxiv · Jan 12, 2024Physiology

ATM-deficient lung, prostate and pancreatic cancer cells are acutely sensitive to the combination of olaparib and the ATR inhibitor AZD6738

N. R. Jette, S. Radhamani, R. Ye, Y. Yu, G. Arthur, S. Goutam, T. Bizmar, M. Kumar, P. Bose, S. Yip, M. Kolinsky, S. P. Lees-MIller

This study shows that ATM-deficient cancer cells are more sensitive to the combination of olaparib and AZD6738, leading to cell death.

bioRxiv · Mar 13, 2020Cancer Biology

The Prorenin Receptor and its Soluble Form Contribute to Lipid Homeostasis

E. Gatineau, G. Arthur, A. Poupeau, K. M. Nichols, B. T. Spear, G. Graf, R. E. Temel, F. Yiannikouris

This study investigates the role of PRR and its soluble form sPRR in lipid homeostasis, finding that hepatic PRR deletion increases cholesterol and sPRR levels, suggesting sPRR contributes to lipid metabolism and adipose-liver communication.

bioRxiv · Jan 27, 2020Physiology