Identification of STK25 as a direct activator of LATS signaling
S. Lim, N. Hermance, T. Mudianto, H. Mustaly, I. P. M. Mauricio, M. A. Vittoria, R. J. Quinton, B. W. Howell, H. Cornils, A. L. Manning, N. J. Ganem
This study identifies STK25 as a novel activator of Hippo signaling by directly phosphorylating LATS, and shows its deletion is common in human cancers.
bioRxiv · Oct 1, 2018Cell Biology