Author

B.-S. Youn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H.-S. Kim· 2 shared I.-H. Kim· 2 shared M. K. Meang· 2 shared S. Kim· 2 shared B. Seong· 1 shared J. Y. Lee· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

H.-S. Kim

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Apoptosis-coupled senescence causes cancer cell senotherapy

B.-S. Youn

This paper identifies ONG41008 as a synthetic polyphenol that induces both senescence and apoptosis in cancer cells while sparing normal cells, potentially offering a novel anti-cancer strategy.

bioRxiv · Sep 22, 2023 · PreprintCancer Biology

A noble TGF beta biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

H.-S. Kim, M. K. Meang, S. Kim, J. Y. Lee, B. Seong, I.-H. Kim, B.-S. Youn

This paper identifies ONG41008 as a TGFβ biogenesis inhibitor with potent anti-fibrotic and anti-inflammatory effects in IPF and inflammatory models.

bioRxiv · Aug 2, 2021 · PreprintCell Biology

A small molecule that promotes cellular senescence prevents fibrogenesis and tumorigenesis in vitro

B.-S. Youn, M. K. Meang, S. Kim, I.-H. Kim, H.-S. Kim

ONG41008 induces senescence and kills fibrotic and cancer cells without harming normal cells, suggesting it could treat fibrotic and tumorigenic diseases.

bioRxiv · Jun 1, 2021Cell Biology