A Phosphorylation Switch Governs KIF11's Mechanical Output During Mitosis
Amila Šemić, Babu J.N. Reddy, Joseph M. Muretta, Sarah E. Vandal, Alex F. Thompson, Cindy L. Fonseca, Steven S. Rosenfeld, Steven P. Gross, Jason K. Stumpff
This study investigates how phosphorylation at Y211 regulates KIF11's mechanical properties during mitosis, showing it modulates motor velocity, force generation, and spindle dynamics.
Proceedings of the National Academy of Sciences · Aug 11, 2026Peer-reviewedCell Biology