ImmunologybioRxiv
The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced exacerbations in cigarette smoke-exposed mice
Magdiel Pérez-Cruz, Bachirou Koné, Rémi Porte…·Philippe Gosset
This study shows that flagellin, a TLR5 agonist, reduces NTHi-induced COPD exacerbations in cigarette smoke-exposed mice by increasing IL-22 and β-defensin2 production.
DOI 10.1371/journal.pone.0236216