Author

Bao Tran

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Abu Hena Mostafa KamaliD· 1 shared Aleksandar MilosavljeviciD· 1 shared Amrit KoiralaiD· 1 shared Angelina Gaspero· 1 shared Anny Xiaobo Zhou· 1 shared Audrey E. ChristianseniD· 1 shared Bolun LiiD· 1 shared Brendan LeeiD· 1 shared

Activity by Year

2014-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Abu Hena Mostafa KamalORCID

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Author profile →

3 papers

Recent·Most cited

Biallelic Variants in KMO Cause a Novel Form of Congenital NAD Deficiency

Nathalie M. Aceves-Ewing, Nanbing Li-Villarreal, Xiaohui Li, Seema R. Lalani, Jill A. Rosenfeld, Varduhi Petrosyan, Aleksandar Milosavljevic, Angelina Gaspero, Denise G. Lanza, Audrey E. Christiansen, Amrit Koirala, Abu Hena Mostafa Kamal, Nagireddy Putluri, Cristian Coarfa, Bao Tran, , Lindsay Catherine Burrage

The paper identifies biallelic KMO variants as a novel cause of congenital NAD deficiency and shows gene x environment interactions in a mouse model.

medRxiv · Aug 27, 2026 · PreprintGenetic & Genomic Medicine

Single-cell full-length transcriptome of human lung reveals genetic effects on isoform regulation beyond gene-level expression

Bolun Li, Thong Luong, Elelta Sisay, Jinhu Yin, Zixuan Zhang, Maryam Vaziripour, Ju Hye Shin, Yongmei Zhao, Bao Tran, Jinyoung Byun, Yafang Li, Chia Han Lee, Maura O'Neill, Þorkell Andrésson, Yoon Soo Chang, , Jiyeon Choi

The paper presents an isoform-level lung cell atlas using single-cell long-read RNA-sequencing, revealing genetic effects on isoform regulation that improve cell-type classification and identify novel variants associated with lung cancer risk.

bioRxiv · Mar 30, 2026 · PreprintGenetics

Preparation of next-generation DNA sequencing libraries from ultra-low amounts of input DNA: Application to single-molecule, real-time (SMRT) sequencing on the Pacific Biosciences RS II.

Castle Raley, David Munroe, Kristie Jones, Yu-Chih Tsai, Yan Guo, Bao Tran, Sujatha Gowda, Jennifer L. Troyer, Daniel R Soppet, Claudia Stewart, Robert Stephens, Jack Chen, TF Skelly, Cheryl Heiner, Jonas Korlach, Dwight Nissley

The paper develops an amplification-free method for preparing DNA sequencing libraries from very low DNA input for PacBio SMRT sequencing, achieving comparable yields with 1000-fold less starting material.

bioRxiv · Mar 25, 2014 · PreprintGenomics