Author

Audrey E. Christiansen

Baylor College of MedicineORCID 0000-0002-4918-7609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Organism:Drosophila· 1

Frequent Co-Authors

Chih‐Wei HsuiD· 4 shared Mary E. DickinsoniD· 4 shared Angelina Gaspero· 3 shared Jason D. HeaneyiD· 3 shared Tara L. RasmusseniD· 3 shared Angela D. HambliniD· 2 shared Ann Marie FlennikeniD· 2 shared Ann‐Marie MalloniD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Chih‐Wei HsuORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Biallelic Variants in KMO Cause a Novel Form of Congenital NAD Deficiency

Nathalie M. Aceves-Ewing, Nanbing Li-Villarreal, Xiaohui Li, Seema R. Lalani, Jill A. Rosenfeld, Varduhi Petrosyan, Aleksandar Milosavljevic, Angelina Gaspero, Denise G. Lanza, Audrey E. Christiansen, Amrit Koirala, Abu Hena Mostafa Kamal, Nagireddy Putluri, Cristian Coarfa, Bao Tran, , Lindsay Catherine Burrage

The paper identifies biallelic KMO variants as a novel cause of congenital NAD deficiency and shows gene x environment interactions in a mouse model.

medRxiv · Aug 27, 2026 · PreprintGenetic & Genomic Medicine

Uncovering Phenotypic Expansion in AXIN2-Related Disorders Using Precision Animal Modeling

Nathalie M. Aceves-Ewing, Denise Grant Lanza, Paul C. Marcogliese, Di Lu, Chih‐Wei Hsu, H Hashimoto, Matthew Gonzalez, Audrey E. Christiansen, Tara L. Rasmussen, Alex J. Ho, Angelina Gaspero, Cher Sha, Mary E. Dickinson, Bo Yuan, Brian J. Shayota, , Andrew B. Crouse

The paper identifies novel AXIN2 variants causing expanded phenotypes in humans and validates their pathogenicity using human, mouse, and fly models.

Genetics in Medicine · Jul 9, 2026Peer-reviewedGenetic & Genomic Medicine

Mendelian gene identification through mouse embryo viability screening

Pilar Cacheiro, Carl Henrik Westerberg, Jesse Mager, Mary E. Dickinson, Lauryl M. J. Nutter, Violeta Muñoz‐Fuentes, Chih‐Wei Hsu, Ignatia B. Van den Veyver, Ann Marie Flenniken, Colin McKerlie, Stephen A. Murray, Lydia Teboul, Jason D. Heaney, K. C. Kent Lloyd, Louise Lanoue, , John Pullinger

The paper identifies novel Mendelian genes by analyzing mouse embryo lethality and linking them to human disease phenotypes and genetic variants.

Genome Medicine · Oct 13, 2022Peer-reviewedGenetic & Genomic Medicine

Human and mouse essentiality screens as a resource for disease gene discovery

Pilar Cacheiro, Violeta Muñoz‐Fuentes, Stephen A. Murray, Mary E. Dickinson, Maja Bućan, Lauryl M. J. Nutter, Kevin A. Peterson, Hamed Haselimashhadi, Ann Marie Flenniken, Hugh Morgan, Henrik Westerberg, Tomasz Konopka, Chih‐Wei Hsu, Audrey E. Christiansen, Denise Grant Lanza, , A. Siddiq

The paper integrates gene essentiality data from human and mouse screens to classify genes into FUSIL categories, identifying developmental lethal genes associated with rare diseases.

Nature Communications · Jan 31, 2020Peer-reviewedGenomics