Author

Denise G. Lanza

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Abu Hena Mostafa KamaliD· 1 shared Aleksandar MilosavljeviciD· 1 shared Amrit KoiralaiD· 1 shared Angelina Gaspero· 1 shared Ashish DograiD· 1 shared Audrey E. ChristianseniD· 1 shared Bao Tran· 1 shared Behnam NabetiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Abu Hena Mostafa KamalORCID

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Author profile →

2 papers

Recent·Most cited

Biallelic Variants in KMO Cause a Novel Form of Congenital NAD Deficiency

Nathalie M. Aceves-Ewing, Nanbing Li-Villarreal, Xiaohui Li, Seema R. Lalani, Jill A. Rosenfeld, Varduhi Petrosyan, Aleksandar Milosavljevic, Angelina Gaspero, Denise G. Lanza, Audrey E. Christiansen, Amrit Koirala, Abu Hena Mostafa Kamal, Nagireddy Putluri, Cristian Coarfa, Bao Tran, , Lindsay Catherine Burrage

The paper identifies biallelic KMO variants as a novel cause of congenital NAD deficiency and shows gene x environment interactions in a mouse model.

medRxiv · Aug 27, 2026 · PreprintGenetic & Genomic Medicine

Reversible in vivo regulation of drug metabolizing enzyme CYP1A2 activity through a dTAG knock-in strategy

Shenzhi Zhou, Xingyu Ji, Hanfeng Lin, Denise G. Lanza, Sung Y. Jung, Jun Liu, Ashish Dogra, Behnam Nabet, Kevin R. MacKenzie, Jin Wang, Martin Matthew Matzuk, Feng Li

This paper introduces a method to reversibly regulate CYP1A2 enzyme activity in mice using a dTAG knock-in strategy, demonstrating its utility in drug metabolism studies.

bioRxiv · May 12, 2026 · PreprintPharmacology & Toxicology