DUSP4 knockdown in BRAF V600E mutant colorectal cancer induces cell cycle arrest and halts tumor growth
Barbara Hopfgartner, Monika Kriz, Donát Alpár, Yvonne Westermaier, Marco H. Hofmann, Ralph A. Neumüller, Sarah Grosche
This study shows that DUSP4 knockdown causes cell cycle arrest and halts tumor growth in BRAF V600E mutant colorectal cancer models but does not lead to tumor regression.
bioRxiv · Jan 15, 2026 · PreprintGenetics