Author

Donát Alpár

Austrian Academy of SciencesORCID 0000-0002-2638-5418Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amelie Kuchler· 1 shared André F. RendeiroiD· 1 shared Barbara Hopfgartner· 1 shared Christian SchmidliD· 1 shared Christoph BockiD· 1 shared Johanna KlughammeriD· 1 shared Linda C. SchusteriD· 1 shared Marco H. HofmanniD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Amelie Kuchler

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJan 15, 2026

DUSP4 knockdown in BRAF V600E mutant colorectal cancer induces cell cycle arrest and halts tumor growth

Barbara Hopfgartner, Monika Kriz, Donát Alpár…·Sarah Grosche

This study shows that DUSP4 knockdown causes cell cycle arrest and halts tumor growth in BRAF V600E mutant colorectal cancer models but does not lead to tumor regression.

DOI 10.64898/2026.01.15.699635

humanexperimental assay

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GenomicsNature MethodsPeer-reviewedJan 18, 2017

Pooled CRISPR screening with single-cell transcriptome read-out

Paul Datlinger, André F. Rendeiro, Christian Schmidl…·Christoph Bock

This paper combines CRISPR genome editing with single-cell RNA sequencing to enable high-throughput screening with complex molecular read-outs.

1,096 citationstop 1%

CRISPR screenscRNA-seq

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