The protein translation initiation machinery is targetable for developing fast-killing therapeutics against the zoonotic Cryptosporidium parvum
Meng Li, Jigang Yin, Dongqiang Wang, Beibei Zou, Guan Zhu
This paper identifies CpeIF4A as a novel drug target for anti-cryptosporidial therapeutics and shows that Roc-A inhibits parasite growth in vitro and in vivo.
PLoS Pathogens · Jul 28, 2025Peer-reviewedMicrobiology