Molecular docking-based screening for novel inhibitors of the human immunodeficiency virus type 1 protease that effectively reduce the viral replication in human cells
Carla N. Mavian, Roxana M. Coman, Xinrui Zhang, Steve Pomeroy, David A. Ostrov, Ben M. Dunn, John W. Sleasman, Maureen M. Goodenow
The paper identifies novel HIV-1 protease inhibitors through molecular docking and in vitro testing, showing reduced viral replication and enhanced antiviral activity when combined with Ritonavir.
bioRxiv · Nov 14, 2020 · PreprintMolecular Biology