A comparison of feature selection methodologies and learning algorithms in the development of a DNA methylation-based telomere length estimator
Trevor Doherty, Emma Louise Dempster, Eilis J. Hannon, Jonathan S. Mill, Richie Poulton, David L. Corcoran, Karen Sugden, Ben Williams, Avshalom Caspi, Terrie E. Moffitt, Sarah Jane Delany, Therese M. Murphy
This study compares feature selection methods and machine learning algorithms to develop a DNA methylation-based telomere length estimator, finding that principal component analysis followed by elastic net regression performs best.
BMC Bioinformatics · May 1, 2023Peer-reviewedBioinformatics