Author

Trevor Doherty

Technological University DublinORCID 0000-0002-1207-7203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Sarah Jane DelanyiD· 2 shared Therese M. MurphyiD· 2 shared Avshalom CaspiiD· 1 shared Ben Williams· 1 shared David L. CorcoraniD· 1 shared Edel McDermott· 1 shared Eilis J. HannoniD· 1 shared Emma Louise DempsteriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Sarah Jane DelanyORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 8, 2025

Analysis of blood-based DNA Methylation signatures of aging and disease progression in IBD patients

Trevor Doherty, Edel McDermott, Sarah Jane Delany…·Therese M. Murphy

This study identifies DNA methylation signatures associated with aging and disease progression in IBD patients, showing that DunedinPACE can distinguish disease activity and recurrence.

DOI 10.1101/2025.02.08.635564

humanDNA methylation

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BioinformaticsBMC BioinformaticsPeer-reviewedMay 1, 2023

A comparison of feature selection methodologies and learning algorithms in the development of a DNA methylation-based telomere length estimator

Trevor Doherty, Emma Louise Dempster, Eilis J. Hannon…·Therese M. Murphy

This study compares feature selection methods and machine learning algorithms to develop a DNA methylation-based telomere length estimator, finding that principal component analysis followed by elastic net regression performs best.

18 citations

DNA methylationstatistical model

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