Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections
Lauren N. McKinley, McCauley O. Meyer, Aswathy Sebastian, Benjamin K Chang, Kyle J. Messina, Istvan U. Albert, Philip C. Bevilacqua
The paper tests over 2,600 natural twister ribozymes using CHiTA, finding 94% are active and showing structural tolerance.
Nucleic Acids Research · Oct 2, 2024Peer-reviewedBiochemistry