Proximity proteomics reveals a co-evolved LRRK2-regulatory network linked to centrosomes
Marita Eckert, Pasquale Miglionico, Francesca Izzi, Natalia De Oliveira Rosa, Benjamin Riebenbauer, Marius Ueffing, Francesco Raimondi, Christian Johannes Gloeckner
This study identifies a LRRK2-regulatory network through proximity proteomics and structural analysis, showing its link to centrosomes and how its conformation and activity state influence interactions.
EMBO Reports · May 23, 2026Peer-reviewedNeuroscience