Kevin Menden

Cellular and Extracellular microRNA Dysregulation in LRRK2-Linked Parkinson's Disease

This study identifies differentially expressed micro-RNAs in LRRK2 G2019S mutation carriers using induced pluripotent stem cell-derived neurons, showing no linear correlation with LRRK2 activity.

A multi-omics dataset for the analysis Frontotemporal Dementia genetic subtypes

The paper presents a multi-omics dataset for genetic subtypes of frontotemporal dementia to identify molecular mechanisms disrupted in the disease.

Pathogen Detection in RNA-Seq Data with Pathonoia

Pathonoia detects viruses and bacteria in RNA-seq data with high precision and recall, outperforming existing methods and providing insights into microbe-host interactions.

Deep-learning-based cell composition analysis from tissue expression profiles.

Scaden is a deep learning model for cell deconvolution that outperforms existing methods and works across bulk RNA-seq, microarray, and human/mouse tissue data.