Neuropeptide CRH prevents premature differentiation of OPCs following CNS injury and in early postnatal development
Clemens Ries, Tibor Štark, Benoit Boulat, Torben Ruhwedel, Jan Philipp Delling, Antonio Miralles Infante, Julia von Poblotzki, A.F. Ulivi, Iven-Alex von Mücke-Heim, Simon Chang, Kenji Sakimura, Keiichi Itoi, Dennis Nestvogel, Alessio Attardo, Michael Czisch, , Jan M. Deussing
This study identifies CRH-expressing OPCs that prevent premature differentiation following CNS injury and in early development, highlighting CRHR1's role in oligodendrogenesis.
Cell Reports · Oct 29, 2025Peer-reviewedNeuroscience