Glutamine transporters regulate prostate cancer radiosensitivity through NUPR1-mediated stress response
Uğur Kahya, Vasyl Lukiyanchuk, Ielizaveta Gorodetska, Matthias M Weigel, Ayşe Sedef Köseer, Berke Alkan, Dragana Savic, Annett Linge, Steffen Löck, Mirko Peitzsch, Ira Skvortsova, Mechthild Krause, Anna Dubrovska
This study shows that glutamine transporters regulate prostate cancer radiosensitivity via NUPR1-mediated stress response, with targeting these transporters enhancing radiosensitivity and improving treatment outcomes.
bioRxiv · Apr 22, 2025 · PreprintCancer Biology