Author

Bert Vogelstein

Primary ORCID profile (0000-0003-0766-3854 · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Bert VogelsteiniD6 papers · Howard Hughes Medical Institute

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Ivana Bozic· 2 shared Martin A Nowak· 2 shared Alvin P Makohon-Moore· 1 shared Bartlomiej Waclaw· 1 shared Christine A Iacobuzio-Donahue· 1 shared Collin Tokheim· 1 shared Jeffrey M Gerold· 1 shared Johannes G Reiter· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Ivana Bozic

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evaluating the Evaluation of Cancer Driver Genes

Collin Tokheim, Nickolas Papadopoulis, Kenneth W Kinzler, Bert Vogelstein, Rachel Karchin

This paper evaluates cancer driver gene prediction methods, showing they vary widely and often produce inconsistent results due to unaccounted mutation rate variability.

bioRxiv · Jun 23, 2016Bioinformatics

Reconstructing phylogenies of metastatic cancers

Johannes G Reiter, Alvin P Makohon-Moore, Jeffrey M Gerold, Ivana Bozic, Krishnendu Chatterjee, Christine A Iacobuzio-Donahue, Bert Vogelstein, Martin A Nowak

This study introduces Treeomics, a tool that accurately reconstructs metastatic cancer phylogenies and disambiguates sequencing artifacts, showing high accuracy across varying sample conditions.

bioRxiv · Apr 11, 2016Cancer Biology

Spatial model predicts dispersal and cell turnover cause reduced intra-tumor heterogeneity

Bartlomiej Waclaw, Ivana Bozic, Meredith E Pittman, Ralph H Hruban, Bert Vogelstein, Martin A Nowak

The paper develops a spatial model showing that short-range cell migration and turnover explain reduced intra-tumor heterogeneity and rapid clonal expansion in cancers.

Nature · Sep 10, 2015Peer-reviewedCancer Biology