A chemical-genetic approach for stress-independent activation of the fission yeast stress-activated protein kinase pathway
Kenneth E. Sawin, Ankita Gupta, Tatiana Dudnakova, Beste Bayrak, Adam Kovac, Domenico Modaffari, Ana I. Rodriguez-Rodriguez, Monique L. Scott, Ye Dee Tay
The paper introduces a new yeast strain, SISA4, for sustained Sty1 kinase activation without external stress and demonstrates its utility in studying SAPK pathway effects.
Wellcome Open Research · Aug 8, 2026Peer-reviewedCell Biology