Author

Domenico Modaffari

Wellcome Centre for Cell BiologyORCID 0000-0003-4317-0328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:fungi (other)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Kenneth E. SawiniD· 2 shared Adam KovaciD· 1 shared Ana I. Rodriguez-RodrigueziD· 1 shared Ankita Gupta· 1 shared Beste Bayrak· 1 shared Edward W. J. WallaceiD· 1 shared Monique L. ScottiD· 1 shared Tatiana DudnakovaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Kenneth E. SawinORCID

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2 papers

Recent·Most cited

Cell BiologyWellcome Open ResearchPeer-reviewedAug 8, 2026

A chemical-genetic approach for stress-independent activation of the fission yeast stress-activated protein kinase pathway

Kenneth E. Sawin, Ankita Gupta, Tatiana Dudnakova…·Ye Dee Tay

The paper introduces a new yeast strain, SISA4, for sustained Sty1 kinase activation without external stress and demonstrates its utility in studying SAPK pathway effects.

DOI 10.12688/wellcomeopenres.27245.1

yeastexperimental assay

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Cell BiologybioRxivPreprintApr 15, 2026

Endosomal hitchhiking and NDR kinase signaling coordinate SsdA-mRNP localization

Domenico Modaffari, Edward W. J. Wallace, Kenneth E. Sawin

This study identifies SsdA-mRNP localization in Aspergillus nidulans hyphae as dependent on endosomal hitchhiking and NDR kinase signaling, revealing spatial regulation during polarized growth.

2 citations

fungi (other)proteomics

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