RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment
Eva Benito, Cemil Kerimoglu, Binu Ramachandran, Tonatiuh Pena‐Centeno, Gaurav Jain, Roman Manuel Stilling, Rezaul Islam, Vincenzo Capece, Qihui Zhou, Dieter Edbauer, Camin Dean, André Fischer
The paper shows that environmental enrichment in adult male mice enhances synaptic plasticity, which is inherited by offspring via sperm RNA, specifically microRNAs 212/132.
Cell Reports · Jan 1, 2018Peer-reviewedNeuroscience