Camin Dean

Sequential visual stimuli increase high frequency power in the visual cortex

The paper shows that sequential visual flickering increases high-frequency power in the visual cortex of mice.

Acute exposure of mouse and human hippocampal slices to tau oligomers reversibly impairs sharp-wave ripples

The paper investigates the effects of tau oligomers on sharp-wave ripples in mouse and human hippocampal slices, finding reversible impairments in SWR parameters depending on species and tau preparation.

A calcium imaging pipeline to detect and quantify compound-specific effects in human and mouse astrocytes and astrocyte-neuron cocultures

The paper develops a calcium imaging pipeline to assess compound effects on astrocyte activity in human and mouse cultures, finding differential responses to drugs and disease models.

A High-Throughput Automated Pipeline to Analyze Synapse Function by Calcium Imaging

This paper introduces a high-throughput automated pipeline for analyzing synaptic function via calcium imaging and demonstrates its sensitivity in detecting synaptic dysfunction.

A human iPS cell line for ready-to-use human iAstrocytes that support human neurons

This paper introduces a human iPSC line that generates iAstrocytes capable of supporting human neuron networks in co-cultures.

A Proof-of-Principle of Nanoscale Optogenetics

This paper demonstrates a proof-of-principle for nanoscale optogenetic activation using a focal stimulation approach with switchable light-gated channels.

Visualizing BDNF cell-to-cell transfer reveals astrocytes are the primary recipient of neuronal BDNF

The paper uses imaging to show astrocytes are the main recipients of neuronally released BDNF, with TrkB levels and neuronal activity influencing uptake and physiological effects.

RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment

The paper shows that environmental enrichment in adult male mice enhances synaptic plasticity, which is inherited by offspring via sperm RNA, specifically microRNAs 212/132.