Rezaul Islam

This study identifies an inflammation-driven gene module in brain endothelial cells that compromises BBB integrity in Alzheimer's disease and shows that an NF-κB inhibitor can reverse these effects.

The paper shows that combining CSF1R inhibition with GENUS stimulation improves cognitive function in Alzheimer's mice by restoring neural circuitry and gene expression.

This study shows that multisensory gamma stimulation improves cognitive function and adult neurogenesis in Ts65Dn mice, a model of Down syndrome.

This study analyzes single-cell transcriptomes of the mouse hippocampus after voluntary exercise, identifying molecular changes related to neurogenesis and signaling pathways.

The paper identifies a novel miR-99b-5p-Zbp1 pathway in microglia that contributes to schizophrenia pathogenesis and suggests potential therapeutic strategies.

This study shows that SETD1B is crucial for learning and regulates neuronal plasticity genes in the postnatal brain through H3K4me3 modification.

The paper isolates synaptic RNA from hippocampal neurons and identifies microRNAs that regulate the synaptic mRNAome, suggesting astrocytic contribution and dynamic regulation.

This study shows heart failure causes hippocampal gene-expression changes leading to memory impairment in mice, and suggests a drug to improve cognition in heart failure patients.

The paper shows that Setd1b regulates neuronal identity genes in the adult brain, affecting cognitive function and memory, with other KMTs compensating for its absence.

The paper shows that environmental enrichment in adult male mice enhances synaptic plasticity, which is inherited by offspring via sperm RNA, specifically microRNAs 212/132.