Cancer BiologyJournal of Thoracic OncologyPeer-reviewed
Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity
Shilpa Singh, Catherine E. Gleason, Min Fang…·Matthew G. Oser
This paper develops cyclin A/B macrocyclic inhibitors that induce apoptosis in cancers with high E2F activity by blocking RxL-mediated interactions, showing efficacy in SCLC models.
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