Molecular BiologybioRxivPreprint
PARP inhibitor synthetic lethality reveals homologous recombination sub-pathway architecture
Ki Choi Chan, Anastasiia Kovina, Johanna Ertl da Costa…·Markus Löbrich
This study uses CRISPR screening to map genetic interactions in homologous recombination sub-pathways, revealing roles of RAD54L, RAD51AP1, RAD54B, and TOP3A in pathway choice and function.
DOI 10.64898/2026.03.06.709881