Molecular Basis for RNA Cytidine Acetylation by NAT10
Mingyang Zhou, Supuni Thalalla Gamage, Khoa A. Tran, David Bartee, Xuepeng Wei, Boyu Yin, Shelley L. Berger, Jordan L. Meier, Ronen Marmorstein
This study determines the cryo-EM structure of NAT10 bound to a cytidine-CoA probe, revealing its mechanism for RNA N4-cytidine acetylation and its role in cellular processes.
Nature Communications · Jun 19, 2026Peer-reviewedBiophysics