A High-Resolution Landscape of Mutations in the BCL6 Super-Enhancer in Normal Human B-Cells
Jiang-Cheng Shen, Ashwini S. Kamath‐Loeb, Brendan F. Kohrn, Keith R. Loeb, Bradley D. Preston, Lawrence A. Loeb
The paper detects subclonal mutations in BCL6 super-enhancers of normal human B-cells using Duplex Sequencing, revealing conserved mutational hotspots linked to lymphomas.
Proceedings of the National Academy of Sciences · Nov 20, 2019Peer-reviewedGenomics