Author

Lawrence A. Loeb

University of WashingtonORCID 0000-0001-6291-4498Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ashwini S. Kamath‐Loeb· 1 shared Bradley D. Preston· 1 shared Brendan F. KohrniD· 1 shared Jiang-Cheng Shen· 1 shared Keith R. LoebiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Ashwini S. Kamath‐Loeb

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1 paper

Recent·Most cited

GenomicsProceedings of the National Academy of SciencesPeer-reviewedNov 20, 2019

A High-Resolution Landscape of Mutations in the BCL6 Super-Enhancer in Normal Human B-Cells

Jiang-Cheng Shen, Ashwini S. Kamath‐Loeb, Brendan F. Kohrn…·Lawrence A. Loeb

The paper detects subclonal mutations in BCL6 super-enhancers of normal human B-cells using Duplex Sequencing, revealing conserved mutational hotspots linked to lymphomas.

25 citations

humanwhole-genome sequencing

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