Author

Keith R. Loeb

University of WashingtonORCID 0000-0002-3305-0261Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alexander K.C. WongiD· 1 shared Ashwini S. Kamath‐Loeb· 1 shared Benjamin J. Hindson· 1 shared Bradley D. Preston· 1 shared Brendan F. KohrniD· 1 shared Christopher M. Hindson· 1 shared Christopher McFarlandiD· 1 shared Don A. Masquelier· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Alexander K.C. WongORCID

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2 papers

Recent·Most cited

A High-Resolution Landscape of Mutations in the BCL6 Super-Enhancer in Normal Human B-Cells

Jiang-Cheng Shen, Ashwini S. Kamath‐Loeb, Brendan F. Kohrn, Keith R. Loeb, Bradley D. Preston, Lawrence A. Loeb

The paper detects subclonal mutations in BCL6 super-enhancers of normal human B-cells using Duplex Sequencing, revealing conserved mutational hotspots linked to lymphomas.

Proceedings of the National Academy of Sciences · Nov 20, 2019Peer-reviewedGenomics

Massively parallel digital transcriptional profiling of single cells

Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark Gregory, Joe Shuga, Luz Montesclaros, Jason G. Underwood, Don A. Masquelier, , Jason H. Bielas

8-channel GemCode droplet barcoding captures ∼50% of loaded cells for 3′ mRNA counting, profiling 68k peripheral blood mononuclear cells and calling transplant chimerism from transcript variants.

Nature Communications · Jan 16, 2017Peer-reviewedGenomics✦ In-depth digest