Human differentiated adipocytes can serve as surrogate mature adipocytes for adipocyte-derived extracellular vesicle analysis
Mangesh Dattu Hade, Bradley L. Butsch, Paola Loreto Palacio, Kim Truc Nguyen, Dharti Shantaram, Sabrena F. Noria, Stacy A. Brethauer, BRADLEY J. NEEDLEMAN, Willa A. Hsueh, Eduardo Reátegui, Setty M. Magaña
The paper shows that human differentiated adipocytes can produce EVs similar to mature adipocytes, providing a reliable alternative for studying adipocyte-derived extracellular vesicles in obesity research.
bioRxiv · Feb 5, 2025 · PreprintCell Biology