Author

Bram M P Verhagen

University Medical Center Utrecht

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Molecular Biology· 1

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Approach:deep learning· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:proteomics· 1

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Carlos AlvaradoiD· 1 shared David LiedtkeiD· 1 shared Eivind ValeniD· 1 shared Jeroen de RidderiD· 1 shared Joseph Daniel PuglisiiD· 1 shared Lucía Barbadilla-Martínez· 1 shared Marvin E. TanenbaumiD· 1 shared Micha Muller· 1 shared

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMay 12, 2026

Decoding the Sequence Requirements for Translation Initiation

Bram M P Verhagen, David Liedtke, Lucía Barbadilla-Martínez…·Marvin E. Tanenbaum

The paper defines an extended translation initiation sequence (eTIS) and shows that a deep-learning model trained on eTIS features accurately predicts translation initiation, revealing that the Kozak sequence is not optimal and identifying conserved nucleotides that enhance initiation efficiency.

2 citations

humanproteomics

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