A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV
Philipp Niklas Ostermann, Youjun Wu, Scott A. Bowler, Samuel Martínez-Meza, Mohammad Adnan Siddiqui, David H. Meyer, Alberto M. Herrera, Brandon A. Sealy, Mega Sidharta, Kiran Ramnarine, Leslie Ann St. Bernard, Desiree Byrd, R. Brad Jones, Masahiro Yamashita, Douglas F. Nixon, , Teresa H. Evering
Direct reprogramming of skin fibroblasts into neurons reveals unique gene signatures indicative of HIV infection in the context of viral suppression.
JCI Insight · Nov 25, 2025Peer-reviewedNeuroscience