Youjun Wu

Direct reprogramming of skin fibroblasts into neurons reveals unique gene signatures indicative of HIV infection in the context of viral suppression.

The paper identifies mitochondria as the transport vehicle for ribosomes to dendrites in C. elegans sensory neurons, showing that MIRO-1 is required for this process.

This study generates human cerebral organoids with a structured outer subventricular zone by activating the STAT3 pathway with LIF, mimicking in vivo oRG development and enhancing neuronal maturation.

This study identifies OGT-mediated O-GlcNAcylation of HK1 as a mechanism regulating glycolytic metabolon assembly on mitochondria, enhancing ATP production and synaptic function.

The paper identifies the CaMKII-Sarm1-ASK1 pathway as a neuroprotective mechanism against axon degeneration caused by mitochondrial loss in C. elegans.