Author

Philipp Niklas Ostermann

University of CologneORCID 0000-0002-4419-6119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Jörg IsenseeiD· 2 shared Rebecca DinnendahliD· 2 shared Tim B. HuchoiD· 2 shared Achim SchmidtkoiD· 1 shared Alberto M. HerreraiD· 1 shared Andreas LeffleriD· 1 shared Brandon A. Sealy· 1 shared Bushra DohaiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Jörg IsenseeORCID

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3 papers

Recent·Most cited

NeurosciencePain Research and ManagementPeer-reviewedJan 1, 2026

Senescence-associated Cdkn1a (p21) is upregulated in rodent dorsal root ganglion neurons across lesion-based neuropathic pain models

Philipp Niklas Ostermann, Rebecca Dinnendahl, Jörg Isensee, Tim B. Hucho

The paper analyzes transcriptome data to show Cdkn1a but not Cdkn2a is upregulated in DRG neurons across neuropathic pain models.

DOI 10.1155/prm/6836731

ratbulk RNA-seq

𝕏 PostBluesky

NeuroscienceJCI InsightPeer-reviewedNov 25, 2025

A Transcriptional Signature of Induced Neurons Differentiates Virologically Suppressed People Living With HIV from People Without HIV

Philipp Niklas Ostermann, Youjun Wu, Scott A. Bowler…·Teresa H. Evering

Direct reprogramming of skin fibroblasts into neurons reveals unique gene signatures indicative of HIV infection in the context of viral suppression.

DOI 10.1172/jci.insight.190445

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 25, 2025

CaV1.2-dependent excitation-transcription coupling modulates nociception

Jörg Isensee, Patrick Engel, Paul Chu Sin Chung…·Tim B. Hucho

This paper investigates Cav1.2-dependent excitation-transcription coupling in nociceptors, showing it modulates pain sensitivity by affecting gene expression and neuronal function.

DOI 10.1101/2025.06.25.661480

mousebulk RNA-seq

𝕏 PostBluesky