Leaflet-specific phospholipid imaging using genetically encoded proximity sensors
William M. Moore, Roberto J. Brea, Caroline H. Knittel, Ellen Wrightsman, Brandon Hui, Jinchao Lou, Christelle F. Ancajas, Michael D. Best, Christopher John Obara, Neal K. Devaraj, Itay Budin
This paper introduces FACES, a tool for imaging lipid pools and transbilayer orientation in living cells, and applies it to study lipid transfer proteins and membrane asymmetry.
Nature Chemical Biology · Sep 15, 2025Peer-reviewedCell Biology