Structural variation detection by proximity ligation from FFPE tumor tissue
Chris J. Troll, Nicholas H. Putnam, Paul D. Hartley, Brandon Rice, Marco Blanchette, Sameed M. Siddiqui, Javkhlan-Ochir Ganbat, Martin P. Powers, Christian A. Kunder, Carlos D. Bustamante, James L. Zehnder, Richard Edward Green, Helio A. Costa
This paper develops a method called Fix-C to detect structural variations in FFPE tumor samples, achieving high concordance with FISH assays and identifying novel variations.
bioRxiv · Feb 27, 2018 · PreprintGenomics