Richard Edward Green

This study uses DNA from museum hair samples to confirm Thomas Jefferson's ancestry in descendants of Sally Hemings and Martha Wayles Jefferson, supporting paternity over alternative explanations.

This study uses ancient and modern bison genomes to show past population connectivity and reveal human impacts on bison diversity, informing conservation efforts.

The paper uses long-read sequencing to identify pathogenic variants in autism cases, finding three pathogenic mutations and nine candidate structural variants missed by short-read sequencing.

Hi-reComb estimates recombination maps from bulk gamete Hi-C data, showing accurate results in fish sperm and enabling structural variant analysis.

This study shows Wolbachia infection changes host cell states in Drosophila cell lines, affecting gene expression and chromatin structure, and suggests these changes determine symbiotic outcomes.

The paper presents haplotype-resolved genomes of six ape species with high accuracy and provides comparative analyses to study evolutionary diversity and gene family evolution.

The paper analyzes genomic data from Beefalo cattle and finds most lack detectable bison ancestry, challenging the breed association's 3/8 bison requirement.

The paper produces gapless assemblies of ape sex chromosomes for five great apes and a lesser ape, revealing divergence in Y chromosomes and evolutionary dynamics.

The paper introduces Minigraph-Cactus, a pangenome pipeline that constructs pangenome graphs directly from whole-genome alignments, demonstrating improved performance in mapping and variant calling across human and Drosophila data.

The paper presents a draft human pangenome reference that improves variant discovery and structural variant detection compared to existing references.

The paper shows recombination between heterologous human acrocentric chromosomes using pangenome data, revealing pseudo-homologous regions linked to Robertsonian translocations.

The paper evaluates sequencing and assembly methods to create high-quality diploid human genome assemblies, finding that long reads and haplotype sorting improve accuracy and completeness.

The paper summarizes methods and lessons from assembling 16 vertebrate genomes, highlights the importance of long-read sequencing, and introduces the Vertebrate Genomes Project to generate complete reference genomes for all vertebrate species.

The paper demonstrates a chromosome-scale genome assembly of a single outbred Drosophila melanogaster using a hybrid method with low input DNA.

The paper presents an optimized PromethION nanopore sequencing method and new computational tools for efficient human genome assembly, achieving high accuracy and speed.

This paper presents a high-quality genome assembly of the saltwater crocodile and identifies genes under positive selection in crocodilians.

The paper shows that inducing DNA breaks accelerates aging-related chromatin changes and loss of cell identity in mammals.

This study uses trio binning to assemble chromosome-length haplotigs for yak and cattle from an F1 hybrid, achieving high continuity and phasing accuracy.

R2C2 improves nanopore read accuracy for full-length single-cell cDNA sequencing, enabling more accurate isoform-level transcriptome analysis.

This study examines how chromosomal rearrangements in the gibbon genome affect TAD boundaries and epigenetic features, finding overlap between rearrangement breakpoints and TAD boundaries.

The paper presents an updated horse reference genome, EquCab3, which improves contiguity and composition compared to the previous version, EquCab2.

This paper develops a method called Fix-C to detect structural variations in FFPE tumor samples, achieving high concordance with FISH assays and identifying novel variations.

The paper analyzes genomic data from passenger pigeons and their relatives to show that natural selection reduced neutral genetic diversity despite large population size, challenging previous extinction theories.