Christian A. Kunder

This study shows aging suppresses lung tumor initiation and growth in mice, with age-dependent effects on tumor suppressor genes like PTEN and persistent age-related transcriptomic changes in tumors.

The paper identifies HBO1 and MLL1 complexes as key tumor suppressors in lung cancer using in vivo functional screens of epigenetic regulators.

STAMPede is a web-based portal for visualizing somatic tumor sequencing data from a solid tumor oncology panel, enabling query and display of gene-, variant-, and cancer-level summary statistics.

The paper develops and validates a targeted RNAseq panel (Fusion-STAMP) for detecting gene fusions in solid tumors, showing high sensitivity and specificity.

This paper develops a method called Fix-C to detect structural variations in FFPE tumor samples, achieving high concordance with FISH assays and identifying novel variations.