Endothelial ACKR1 expression regulates neutrophil infiltration and breast cancer metastatic engraftment in the lung metastatic niche
S. Tanner Roach, Qianxun Wang, Rishi Patel, Serena Thomas, Braulio Aguilar, Chinwe Obianuju Ewenighi, Lauren Raasch, William A. Müller, L.A. Naiche, Jan Kitajewski
This study shows that endothelial ACKR1 promotes neutrophil infiltration and breast cancer metastasis in the lung by facilitating tumor cell engraftment.
bioRxiv · Mar 18, 2026 · PreprintCancer Biology