Dynamics of age-related catastrophic mitotic failures and recovery in yeast
Matthew M. Crane, Adam E. Russell, Brent J Schafer, Mung Gi Hong, Joslyn E Goings, Kenneth L. Chen, Ben W. Blue, Matt R. Kaeberlein
This study uses single-cell imaging to examine age-related genome missegregation in yeast, identifying rDNA expansion as a contributor to mitotic failures and nucleolar breakdown.
bioRxiv · Nov 9, 2018 · PreprintCell Biology