Principled Feature Attribution for Unsupervised Gene Expression Analysis
Joseph D. Janizek, Anna E. Spiro, Safiye Çelik, Ben W. Blue, Joshua C. Russell, Ting-I Lee, Matt Kaeberlin, Su‐In Lee
This paper introduces a novel unsupervised pathway attribution method that identifies major transcriptomic variation sources when combined with biologically-constrained models, applied to Alzheimer's disease brain samples.
bioRxiv · May 3, 2022 · PreprintBioinformatics