Author

Brian C Bond

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Bo JiniD· 1 shared Caroline Benn· 1 shared Christian LandlesiD· 1 shared Edward J. SmithiD· 1 shared Georgina F OsborneiD· 1 shared Gillian P. BatesiD· 1 shared Iulia M NitaiD· 1 shared Jemima M PhillipsiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Bo JinORCID

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1 paper

Recent·Most cited

A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease

Sarah G. Aldous, Edward J. Smith, Christian Landles, Georgina F Osborne, María Cañibano-Pico, Iulia M Nita, Jemima M Phillips, Yongwei Zhang, Bo Jin, Marissa B. Hirst, Caroline Benn, Brian C Bond, Winfried Edelmann, Jonathan R. Greene, Gillian P. Bates

This study shows that reducing MSH3 in Huntington's disease mouse models prevents somatic CAG repeat expansion but does not accelerate disease onset, suggesting somatic expansion may not be required for pathogenesis.

Brain · Feb 21, 2024Peer-reviewedNeuroscience