Humanized FLT3 mice display enhanced tissue engraftment and support HIV-1 persistence and rebound
Patricia Resa‐Infante, Patricia Pinol, Fernando Laguía, Gerard Campos-Gonzalez, Àlex Cobos, Víctor Urrea, Maria C. García-Guerrero, Yaiza Rosales, Cid Marina, Jorge Dı́az, Leonard D. Shultz, Voot Yin, Michael A. Brehm, Brian W. Soper, María Salgado, Javier Martínez‐Picado
This study introduces a novel humanized FLT3 mouse model that supports enhanced development of human innate immune cells and HIV-1 persistence, mimicking human viral reservoirs.
Translational research · Aug 12, 2026Peer-reviewedImmunology