Author

Brihget Sicairos

University of Arkansas at Fayetteville

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Jianhong ZhouiD· 1 shared Qingyang ZhangiD· 1 shared Wei Q. ShiiD· 1 shared Yuchun DuiD· 1 shared Zhijian HuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperCancer Biology

Jianhong ZhouORCID

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1 paper

Recent·Most cited

Cancer BiologyACS OmegaPeer-reviewedAug 19, 2025

Proteomic analysis reveals the dominant effect of ipomoeassin F on the synthesis of membrane and secretory proteins in triple-negative breast cancer cells

Brihget Sicairos, Jianhong Zhou, Zhijian Hu…·Yuchun Du

This study uses proteomic analysis to show that ipomoeassin F inhibits membrane and secretory protein synthesis in TNBC cells by targeting Sec61, leading to cell proliferation and survival crisis.

DOI 10.1021/acsomega.5c02784

humanproteomics

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