Qingyang Zhang

This study uses proteomic analysis to show that ipomoeassin F inhibits membrane and secretory protein synthesis in TNBC cells by targeting Sec61, leading to cell proliferation and survival crisis.

The paper presents an in silico method to classify and identify co-purified protein complexes using cryoEM data, revealing new structures and multiple membrane scaffold protein assembly states.

This paper introduces a Gaussian copula-based method for RNA-Seq classification that accounts for gene dependencies, improving accuracy over independence-based models.