A MET-Targeted Variable New Antigen Receptor Theranostic for Non-Small Cell Lung Cancer
Rachel L. Minne, Jayden L. West, Natalie Y. Luo, Kwangok P. Nickel, Gihan S. Gunaratne, Kendahl L. Ott, Joseph P. Gallant, Kendall E. Barrett, Caroline Mörk, Saahil Javeri, Madalynn R. Wopat, Loren D. Rivera Lopez, Will Toscano, Nina C. Zitzer, Ohyun Kwon, , Aaron Matthew LeBeau
This paper develops a shark-derived VNAR-based theranostic agent for MET-altered NSCLC, showing imaging and therapeutic efficacy in preclinical models.
bioRxiv · Mar 11, 2026 · PreprintCancer Biology