Kwangok P. Nickel

This paper develops a shark-derived VNAR-based theranostic agent for MET-altered NSCLC, showing imaging and therapeutic efficacy in preclinical models.

This study identifies PRAME as a therapeutic target in NUT carcinoma, showing its high expression and susceptibility to T-cell mediated cytotoxicity via PRAME epitopes presented by HLA Class I molecules.

The paper shows that higher chromosomal instability (CIN) in cancer cells and tumors increases sensitivity to radiation, both directly and through drug-induced CIN mechanisms.